All holes are pre-drilled except the pick-guard. But, remember this is a vintage body so the holes for the neck pickup are also pre-drilled. I set this up as a vintage Tele with a 5-hole pickguard and the neck pickup mounted into the guitar. It also only takes vintage sized bridges so I installed a vintage 3 saddle Gotoh bridge. I used a Fender roasted maple neck with medium tall frets and it fit perfectly. I installed a vintage custom shop 1962 neck pickup and vintage custom shop Broadcaster bridge pickup with no problems. Beautiful finished product- a modern blackguard that plays beautifully.